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Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different

Xin Zou, Ke Chen, Jiawei Zou, Peiyi Han, Jie Hao, Zeguang Han

Frontiers of Medicine   Pages 185-192 doi: 10.1007/s11684-020-0754-0

Abstract: To construct a risk map of different human organs, we analyzed the single-cell RNA sequencing (scRNA-seqthe organs at risk, such as lung, heart, esophagus, kidney, bladder, and ileum, and located specific cell

Keywords： 2019-nCoV     ACE2     single-cell RNA-seq    

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Zinc Air Fuel Cell Power Station

Zhu Mei,Xu Xianzhi,Su Run

Strategic Study of CAE 2004, Volume 6, Issue 12,   Pages 62-64

Abstract:

More and more people pay attention to the electric power generation technology using fuel cells.The zinc-air fuel cell power station technology is introduced in this paper.The detachable electrode technology is employed for manufacturing the largest single cell in the worldAnother character of the power station is the separation circulation technology, which improves the general

Keywords： fuel cell     zinc-air fuel cell     detachable electrode     single cell     separation circulation technology    

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Distinct immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cellRNA-seq analysis

Frontiers of Medicine doi: 10.1007/s11684-023-1017-7

Abstract: By conducting single-cell RNA-seq analyses on 26 gliomas, we reported their classification into primitiveoligodendrocyte precursor cell (pri-OPC)-like and radial glia (RG)-like tumors and validated it in aFor example, glial/glioma stem cell markers OLIG1/PTPRZ1 and B cell-specific receptors

Keywords： single-cell RNA-seq     glioma     radial glia     primitive oligodendrocyte precursor cell     immune escape    

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Transmembrane transport of polycyclic aromatic hydrocarbons by bacteria and functional regulation of membrane proteins

Hongqi Wang, Ruhan Jiang, Dekang Kong, Zili Liu, Xiaoxiong Wu, Jie Xu, Yi Li

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 1, doi: 10.1007/s11783-019-1188-2

Abstract: Proteomics technology such as iTRAQ labeling was used to access expressed proteins.Single cell analysis technology wereused to study the morphological structure.Meanwhile, introduce the proteomics and single cell analysis technology used to address these areas ofAdditionally, analyze the changes in morphology and structure and the characteristics of microbial cellFinally, recognize the microscopic mechanism of PAHs biodegradation in terms of cell and membrane proteins

Keywords： transport     Adsorption and uptake of hydrocarbons     Proteomics     Functional regulation of membrane protein     Singlecell analysis technology    

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Emerging Trends for Microbiome Analysis: From Single-Cell Functional Imaging to Microbiome Big Data

Jian Xu, Bo Ma, Xiaoquan Su, Shi Huang, Xin Xu, Xuedong Zhou, Wei Huang, Rob Knight

Engineering 2017, Volume 3, Issue 1,   Pages 66-70 doi: 10.1016/J.ENG.2017.01.020

Abstract: In this perspective, we argue that in the next decade, method development in microbiome analysis willa consortium or population of cells to probing individual cells; and ③ a shift from microbiome data analysis

Keywords： Microbiome     Methoddevelopment     Single-cell analysis     Big data     China Microbiome Initiative    

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Computer-Aided Design System for CP Single-Screw Compressor

SHEN Jing-feng, YAO Fu-sheng

Frontiers of Mechanical Engineering 2006, Volume 1, Issue 1,   Pages 21-25 doi: 10.1007/s11465-005-0018-3

Abstract:

To design various optimum parameters and simulate the working process of CP single-screw compressor, the Computer-Aided Design (CAD) system for the CP single-screw compressor has been established.A new method based on computer graphics technology, database technology, object-oriented programmingtechnology, and visual simulation technology has been adopted in this CAD system.The experimental results show that the CAD system for the CP single-screw compressor is practical and

Keywords： CP single-screw     database technology     simulation technology     programming technology     animator simulation    

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Distinct mononuclear diploid cardiac subpopulation with minimal cell–cell communications persists in

Frontiers of Medicine   Pages 939-956 doi: 10.1007/s11684-023-0987-9

Abstract: end, 12 645 cardiac cells were generated from embryonic day 17.5 and postnatal days 2 and 8 mice by single-cellMNDCMs having interactions with macrophages and non-proliferative MNDCMs (non-pMNDCMs) with minimal cell–cell Single-nucleus RNA sequencing and immunohistochemical staining further proved that the Myl4single-cell transcriptomic data.In conclusion, a novel non-pMNDCM subpopulation with minimal cell–cell communications was unveiled, highlighting

Keywords： mononuclear diploid cardiomyocytes     cell–cell communication     cardiac fibroblast     single-cell RNA sequencing    

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PathogenTrack and Yeskit: tools for identifying intracellular pathogens from single-cell RNA-sequencing

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 251-262 doi: 10.1007/s11684-021-0915-9

Abstract: Taking advantage of single-cell RNA-sequencing (scRNA-seq) analysis, we can assess the transcriptomicfeatures at the single-cell level.Still, the tools used to interpret pathogens (such as viruses, bacteria, and fungi) at the single-cellcomputational pipeline that uses unmapped scRNA-seq data to identify intracellular pathogens at the single-cellthe state-of-the-art tools such as Viral-Track, and the first tools for identifying bacteria at the single-cell

Keywords： scRNA-seq     intracellular pathogen     microbe     COVID-19     SARS-CoV-2    

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Design and analysis of partially decoupled translational parallel mechanisms with single-loop structures

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 3, doi: 10.1007/s11465-022-0695-1

Abstract: This study presents a family of novel translational parallel mechanisms (TPMs) with single-loop topologicalFirst, a position analysis is performed and validated through numerical simulation to reveal the characteristics

Keywords： translational parallel mechanism     single loop     multiple driving system     workspace analysis     singularity    

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Clinical characteristics and prognostic factors of patients with mature T-cell lymphoid malignancies:a single-institution study of 225 cases

Wen Xue,Yan Sheng,Xiangqin Weng,Yongmei Zhu,Yan Zhao,Pengpeng Xu,Xiaochun Fei,Xiaoyan Chen,Li Wang,Weili Zhao

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 468-477 doi: 10.1007/s11684-015-0419-6

Abstract:

Mature T-cell lymphoid malignancies comprise a group of heterogeneous diseases that vary in clinicopathologicalBone marrow (BM) infiltration is more commonly present in mature T-cell lymphoid malignancies comparedwith their B-cell counterparts and hence important for differential diagnosis.lymphoid malignancies treated in a single institution.Multivariate analysis indicated that poor performance status, advanced disease stage, elevated serum

Keywords： mature T-cell lymphoid malignancies     clonal T-cell population     bone marrow infiltration     prognostic factors    

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Numerical analysis of bearing behaviors of single batter piles under horizontal loads in various directions

Frontiers of Structural and Civil Engineering 2023, Volume 17, Issue 2,   Pages 224-237 doi: 10.1007/s11709-022-0914-1

Abstract: The horizontal bearing behavior of a single batter pile (SBP) is vital to its application in practicalhorizontal loads in various directions at full scale are analyzed comprehensively via finite-element (FE) analysisMoreover, an empirical design method is proposed based on the FE analysis results to predict the bearing

Keywords： single batter pile     skew horizontal load     model test     finite-element analysis     empirical design method    

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Effects of vitrification and cryostorage duration on single-cell RNA-Seq profiling of vitrified-thawed

Ying Huo, Peng Yuan, Qingyuan Qin, Zhiqiang Yan, Liying Yan, Ping Liu, Rong Li, Jie Yan, Jie Qiao

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 144-154 doi: 10.1007/s11684-020-0792-7

Abstract: vitrified-thawed oocytes (3, 3, 4, and 3 oocytes were cryostored for 1, 2, 3, and 12 months) were analyzed at a single-cellFurther analysis revealed that the aberrant genes in the vitrified oocytes were closely related to oogenesis

Keywords： human metaphase II oocyte     vitrification     cryostorage duration     single-cell RNA-Seq     lncRNA    

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A cytoprotective graphene oxide-polyelectrolytes nanoshell for single-cell encapsulation

Luanying He, Yulin Chang, Junhao Zhu, Ying Bi, Wenlin An, Yiyang Dong, Jia-Hui Liu, Shihui Wang

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 2,   Pages 410-420 doi: 10.1007/s11705-020-1950-9

Abstract: Graphene oxide (GO) has been increasingly utilized in the fields of food, biomedicine, environment and other fields because of its benign biocompatible. We encapsulated two kinds of GO with different sizes on yeast cells with the assistance of polyelectrolytes poly (styrene sulfonic acid) sodium salt (PSS) and polyglutamic acid (PGA) (termed as Y@GO). The result does not show a significant difference between the properties of the two types of Y@GO (namely Y@GO1 and Y@GO2). The encapsulation layers are optimized as Yeast/PGA/PSS/PGA/GO/PGA/PSS based on the morphology, dispersity, colony-forming unit, and zeta potential. The encapsulation of GO increases the roughness of the yeast. It is proved that the Y@GO increases the survival time and enhance the activity of yeast cells. The GO shell improves the resistance of yeast cells against pH and salt stresses and extends the storage time of yeast cells.

Keywords： GO     yeast     polyelectrolyte     cytoprotection     nanomaterials    

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intravenous busulfan conditioning with post-transplantation cyclophosphamide for allogeneic peripheral stem celltransplantation for adult patients with lymphoid malignancies: a prospective single-arm phase II study

Ling Wang, Lining Wang, Xing Fan, Wei Tang, Jiong Hu

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 108-115 doi: 10.1007/s11684-019-0730-8

Abstract: immunosuppressive drugs has emerged as a promising strategy in the setting of allogeneic hematopoietic stem cellcyclosporine as graft-versus-host disease (GVHD) prophylaxis after myeloablative conditioning and T cell-repleteperipheral stem cell transplantation in lymphoid malignancies.This single-arm phase II clinical trial (NCT01435447) involving 31 adult patients was conducted from

Keywords： post-transplantation cyclophosphamide     allogeneic hematopoietic stem cell transplantation     lymphoid malignancies    

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Operation analysis of a Chebyshev-Pantograph leg mechanism for a single DOF biped robot

Conghui LIANG, Marco CECCARELLI, Yukio TAKEDA

Frontiers of Mechanical Engineering 2012, Volume 7, Issue 4,   Pages 357-370 doi: 10.1007/s11465-012-0340-5

Abstract:

In this paper, operation analysis of a Chebyshev-Pantograph leg mechanism is presented for a singleA prototype of a single DOF biped robot equipped with two proposed leg mechanisms has been built at LARM

Keywords： biped robots     leg mechanisms     simulation    

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Title Author Date Type Operation

Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different

Xin Zou, Ke Chen, Jiawei Zou, Peiyi Han, Jie Hao, Zeguang Han

Journal Article

Zinc Air Fuel Cell Power Station

Zhu Mei,Xu Xianzhi,Su Run

Journal Article

Distinct immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cellRNA-seq analysis

Journal Article

Transmembrane transport of polycyclic aromatic hydrocarbons by bacteria and functional regulation of membrane proteins

Hongqi Wang, Ruhan Jiang, Dekang Kong, Zili Liu, Xiaoxiong Wu, Jie Xu, Yi Li

Journal Article

Emerging Trends for Microbiome Analysis: From Single-Cell Functional Imaging to Microbiome Big Data

Jian Xu, Bo Ma, Xiaoquan Su, Shi Huang, Xin Xu, Xuedong Zhou, Wei Huang, Rob Knight

Journal Article

Computer-Aided Design System for CP Single-Screw Compressor

SHEN Jing-feng, YAO Fu-sheng

Journal Article

Distinct mononuclear diploid cardiac subpopulation with minimal cell–cell communications persists in

Journal Article

PathogenTrack and Yeskit: tools for identifying intracellular pathogens from single-cell RNA-sequencing

Journal Article

Design and analysis of partially decoupled translational parallel mechanisms with single-loop structures

Journal Article

Clinical characteristics and prognostic factors of patients with mature T-cell lymphoid malignancies:a single-institution study of 225 cases

Wen Xue,Yan Sheng,Xiangqin Weng,Yongmei Zhu,Yan Zhao,Pengpeng Xu,Xiaochun Fei,Xiaoyan Chen,Li Wang,Weili Zhao

Journal Article

Numerical analysis of bearing behaviors of single batter piles under horizontal loads in various directions

Journal Article

Effects of vitrification and cryostorage duration on single-cell RNA-Seq profiling of vitrified-thawed

Ying Huo, Peng Yuan, Qingyuan Qin, Zhiqiang Yan, Liying Yan, Ping Liu, Rong Li, Jie Yan, Jie Qiao

Journal Article

A cytoprotective graphene oxide-polyelectrolytes nanoshell for single-cell encapsulation

Luanying He, Yulin Chang, Junhao Zhu, Ying Bi, Wenlin An, Yiyang Dong, Jia-Hui Liu, Shihui Wang

Journal Article

intravenous busulfan conditioning with post-transplantation cyclophosphamide for allogeneic peripheral stem celltransplantation for adult patients with lymphoid malignancies: a prospective single-arm phase II study

Ling Wang, Lining Wang, Xing Fan, Wei Tang, Jiong Hu

Journal Article

Operation analysis of a Chebyshev-Pantograph leg mechanism for a single DOF biped robot

Conghui LIANG, Marco CECCARELLI, Yukio TAKEDA

Journal Article